Lynyrd Skynyrd founder member Gary Rossington dies,Gary Rossington, Lynyrd Skynyrd’s last surviving original member who also helped to found the group, has died at the age of 71.
Lynyrd Skynyrd founder member Gary Rossington dies
Gary Rossington, Lynyrd Skynyrd’s last surviving original member who also helped to found the group, has died at the age of 71.
Structural basis of mitochondrial membrane bending by the I鈥揑I鈥揑II2鈥揑V2 supercomplex,Mitochondrial energy conversion requires an intricate architecture of the inner mitochondrial membrane1. Here we show that a supercomplex containing all four respiratory chain components contributes to membrane curvature induction in ciliates. We report cryo-electron microscopy and cryo-tomography structures of the supercomplex that comprises 150 different proteins and 311 bound lipids, forming a stable 5.8-MDa assembly. Owing to subunit acquisition and extension, complex I associates with a complex IV dimer, generating a wedge-shaped gap that serves as a binding site for complex II. Together with a tilted complex III dimer association, it results in a curved membrane region. Using molecular dynamics simulations, we demonstrate that the divergent supercomplex actively contributes to the membrane curvature induction and tubulation of cristae. Our findings highlight how the evolution of protein subunits of respiratory complexes has led to the I–II–III2–IV2 supercomplex that contributes to the shaping of the bioenergetic membrane, thereby enabling its functional specialization. A supercomplex comprising all four respiratory chain components contributes to the induction of mitochondrial membrane curvature and tubulation of cristae. Tags:alexanderBaradaranCryoelectron microscopyCryoelectron tomographyFlygaardGruhlHaapanenhumanities and social sciencesM&252;hleipmultidisciplinaryNaturenature.comOutiRasmus KockRozbehscienceStructural biologythomas
Continent-wide declines in shallow reef life over a decade of ocean warming,Human society is dependent on nature1,2, but whether our ecological foundations are at risk remains unknown in the absence of systematic monitoring of species’ populations3. Knowledge of species fluctuations is particularly inadequate in the marine realm4. Here we assess the population trends of 1,057 common shallow reef species from multiple phyla at 1,636 sites around Australia over the past decade. Most populations decreased over this period, including many tropical fishes, temperate invertebrates (particularly echinoderms) and southwestern Australian macroalgae, whereas coral populations remained relatively stable. Population declines typically followed heatwave years, when local water temperatures were more than 0.5 °C above temperatures in 2008. Following heatwaves5,6, species abundances generally tended to decline near warm range edges, and increase near cool range edges. More than 30% of shallow invertebrate species in cool latitudes exhibited high extinction risk, with rapidly declining populations trapped by deep ocean barriers, preventing poleward retreat as temperatures rise. Greater conservation effort is needed to safeguard temperate marine ecosystems, which are disproportionately threatened and include species with deep evolutionary roots. Fundamental among such efforts, and broader societal needs to efficiently adapt to interacting anthropogenic and natural pressures, is greatly expanded monitoring of species’ population trends7,8. A systematic census at 1,636 sites around Australia from 2008 to 2021 finds that more than 30% of shallow invertebrate species in cool latitudes exhibit a high extinction risk due to declining populations and oceanic barriers, but tropical coral species remain relatively stable. Tags:barrettClimate change ecologyedgarEmreenvironmental impactFreddie J.Graham J.heatherhumanities and social sciencesMacroecologymultidisciplinaryNaturenature.comNeville S.Rick D.scienceStuart SmithTurak
Lisa Smyth: GP surgery struggles are no surprise after lack of workforce planning… now cost-of-living crisis will force doctors to scale back services even more,That two more GP surgeries have handed back their contracts to the Department of Health in recent days is hugely concerning. However, it should not come as a surprise to anyone. Tags:articlebelfasttelegraphbelfasttelegraph.co.uklatestNewsNews & Analysisopinion
David Moyes hails West Ham’s European history-maker Jarrod Bowen,David Moyes hailed history maker Jarrod Bowen after he equalled West Ham’s all-time European goalscoring record in the 2-1 win over Anderlecht. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukFootballpopularSportSports
Co Antrim software firm Decision Time now has 50 Irish state agency customers after string of new business wins,Co Antrim software firm Decision Time now has 50 Irish state agency customers after string of new business wins,Co Antrim software company Decision Time now has 50 Irish state agency customers after a string of new business wins, it has announced. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukBUSINESSNewsNorthern Irelandpodcasts
Paula McIntyre’s loaves and the fish: sourdough with mushrooms and plaice with pickled cucumber,During the lockdown it seemed everyone was making sourdough bread. Yeast was in short supply and the obvious solution was to go back to the original way we made bread. It’s naturally leavened which means it doesn’t use yeast to rise but a “starter” is used instead. This involves fermenting flour and water to produce wild yeast and good bacteria. Like commercial yeast it will cause the bread to rise but will give it a tangy flavour and more structured texture. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukEditor's PicksFood and Drinklifelifestyle
Harry claims in Netflix trailer people were ‘happy to lie’ to protect William,Harry claims in Netflix trailer people were ‘happy to lie’ to protect William,The Duke of Sussex has claimed in a new trailer for part two of Harry & Meghan that people were “happy to lie” to protect his brother, the Prince of Wales. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukNewsUK
John Mulgrew: Mini-budget 2022 – Boost for big business but much still to do to help NI private sector and households,In many ways there was nothing ‘mini’ about Kwasi Kwarteng’s financial statement to a packed House of Commons this morning. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukBUSINESSlatestNewsUlster Business
David Bowie’s drummer reflects on singer’s legacy as Walk of Fame stone unveiled,David Bowie’s drummer hailed the late singer as “one of the most amazing artists that has come out in history” as he unveiled a stone on the Music Walk of Fame in London honouring him. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukEntertainmentlatestMusic and Gigs
Gareth Southgate: England must be completely ruthless from now until World Cup,Gareth Southgate says England must be “completely ruthless” from here on out as World Cup preparations ramp up on the back of June’s chastening Nations League results. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukFootballpopularSportSports
Frank Coughlan: If Wolfe Tone was alive today, would he be impressed by chants of ‘Ooh ah, up the Ra’ from a band bearing his name?,There’s an app for everything these days. So I’m told by millennials. As if any problem in my world can be solved by a simple download. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukCommentIRA (Terrorist Organisation)opinion
Cleverly talks shambles is yet another missed opportunity for progress,On Tuesday, one could be forgiven for having a glimmer of hope that progress on the Stormont political stalemate could soon be made. Tags:aarticlebelfasttelegraphbelfasttelegraph.co.uknopinion
NI guitarist Simon McBride joins legendary rock band Deep Purple,Northern Ireland man Simon McBride has officially become a permanent member of rock royalty Deep Purple, after filling in for veteran guitarist Steve Morse over the last year. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukEntertainmentMusic and Gigsreviews
Queen’s funeral will be a beautiful day, says Master of the King’s Music,The Queen’s state funeral will be a day that highlights the “wonderful things that can happen in music”, the Master of the King’s Music has said. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukEditor's PicksNewsUK
Elliot Daly among England squad winners as Billy Vunipola and Jonny May lose out,New England head coach Steve Borthwick has named his first squad since replacing Eddie Jones last month. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukrugbySport
Rangers manager Michael Beale criticises Hampden Park pitch as semi-final win sets up Old Firm cup final,Rangers manager Michael Beale called for Scottish football to present itself better after his team’s Viaplay Cup semi-final win over Aberdeen was marred by a poor Hampden pitch and a VAR failure. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukCeltic FCFootballRangers FCSport
Mid-air sexual assault man avoids jail after incident on NI flight to Faro,A man who sexually assaulted a female cabin crew member mid-air has narrowly escaped a prison sentence. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukNewsSunday Life
David Harewood made OBE after raising awareness of mental health and racism,Actor and broadcaster David Harewood has been made an OBE in the New Year Honours list after becoming a prominent voice for better mental health support. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukEntertainmentFilm and TV
Orla Chennaoui: I’m abandoning pointless New Year’s resolutions… instead here are some alternatives you’re welcome to steal,New Year’s resolutions are a funny old tradition. They’re like an ancient form of manifestation, before manifestation was a thing. Make a life wishlist, set it to one side, and revisit this time next year to see all the ways in which one has failed. Or is that just me? Tags:articlebelfasttelegraphbelfasttelegraph.co.uklifeWeekend
Jacinda Ardern announces shock resignation as New Zealand Prime Minister,Jacinda Ardern has announced her shock resignation as New Zealand Prime Minister, saying she “no longer has enough in the tank” to do the role justice. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukNewsWORLD
Antonio Conte warns World Cup winner Cristian Romero of heightened expectations,Antonio Conte is delighted to have Tottenham’s World Cup winner Cristian Romero available again but has warned the defender a “difficult period” lies ahead. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukFootballSport
Rosalind Skillen: Nature depletion is pushing some of our bird populations to brink of extinction,The rapid decline of bird species across the UK and Ireland is just one of the signs that we are hurtling towards a nature-depleted world. I don’t know about you, but a world with no stable natural environment, no biodiversity and no wildlife is not one that I wish to inhabit. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukclimate changeColumnistsopinion
Mikel Arteta optimistic Arsenal will secure William Saliba contract extension,Mikel Arteta is optimistic Arsenal will be able to secure a contract extension to ensure defender William Saliba remains a Gunner long term. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukFootballSport
Staycations: Where to catch a break in Ireland this year,If holidaying around Ireland is on your 2023 to-do list, here are 43 accommodation deals whether you’re opting for hotels, cottages or yurts and geodomes... Tags:aarticlebelfasttelegraphbelfasttelegraph.co.uknTravel
Frank Mitchell: Will three be the magic number for the coming year? Only tell will tell...,It’s difficult to get excited about a year ending in a three. It doesn’t have the ring of those that have gone before. Years 2020, 2021 and 2022 had a rhythm to their numbering but of course they turned out to be a hard slog. They were bumpy challenging years blighted by both Covid and our adapting to Brexit. Tags:articlebelfasttelegraphbelfasttelegraph.co.ukChristmasIRA (Terrorist Organisation)lifeWeekend
Three ways moving on from Aaron Rodgers impacts Packers
Three ways moving on from Aaron Rodgers impacts Packers,Moving on from a franchise quarterback is a challenging situation for any NFL team. Here are three ways the Packers will be impacted if Rodgers has indeed played his last game as a member of the
DOH warns vs eating seafood from oil spill areas
DOH warns vs eating seafood from oil spill areas,The Department of Health warned the public yesterday against eating fish and other seafood from areas affected by the oil spill.
The post DOH warns vs eating seafood from oil spill areas appeared first
Washington turns to Wall Street to help rescue dying bank
Washington turns to Wall Street to help rescue dying bank,In a scene reminiscent of the last financial crisis, the federal government turned to Wall Street this week for help with a blossoming emergency in the banking sector
Birds sometimes hitch rides on ships—and it's changing the way they migrate,Freighter crews have long told stories of sparrows and nightjars, owls, and herons settling on their boats’ decks. Tags:AnimalsBirdsEnvironmentpopsci.comPopular ScienceWildlife
What we know about hormonal birth control and breast cancer risk,Don't throw out your birth control pills just yet—studies show this risk disappears eventually after stopping hormonal birth control. Tags:CancerdiseasesHealthmedicinepopsci.comPopular ScienceScience
What ancient tsunamis can teach us about future disasters,Gigantic tsunamis have been decimating coastlines since time immemorial. We ignore these prehistoric warnings at our own peril. Tags:Environmentpopsci.comPopular ScienceScienceweather
