Slipknot New Bassist: Alessandro Venturella's Identity Discovered in Band's LP Through These?,Slipknot's fans reportedly identified its new bassist, Alessandro "Vman" Venturella, because of his "distinctive" body part.#SlipKnot #AlessandroVenturella
Slipknot New Bassist: Alessandro Venturella's Identity Discovered in Band's LP Through These?
Slipknot's fans reportedly identified its new bassist, Alessandro "Vman" Venturella, because of his "distinctive" body part.#SlipKnot #AlessandroVenturella
Reconstruction and deconstruction of human somitogenesis in vitro,The vertebrate body displays a segmental organization which is most conspicuous in the periodic organization of the vertebral column and peripheral nerves. This metameric organization is first implemented when somites, which contain the precursors of skeletal muscles and vertebrae, are rhythmically generated from the presomitic mesoderm (PSM). Somites then become subdivided into anterior and posterior compartments essential for vertebral formation and segmental patterning of the peripheral nervous system1–4. How this key somitic subdivision is established remains poorly understood. Here we introduce novel tridimensional culture systems of human pluripotent stem cells (PSCs), called Somitoids and Segmentoids, which recapitulate the formation of somite-like structures with antero-posterior (AP) identity. We identify a key function of the segmentation clock in converting temporal rhythmicity into the spatial regularity of anterior and posterior somitic compartments. We show that an initial salt-and-pepper expression of the segmentation gene MESP2 in the newly formed segment is transformed into compartments of anterior and posterior identity via an active cell sorting mechanism. Our work demonstrates that the major patterning modules involved in somitogenesis including the clock and wavefront, AP polarity patterning and somite epithelialization can be dissociated and operate independently in our in vitro systems. Together we define a novel framework for the symmetry breaking process initiating somite polarity patterning. Our work provides a valuable platform to decode general principles of somitogenesis and advance knowledge of human development. Tags:AlessandroDe SimoneDjeffalhumanities and social sciencesJong GwanKongjuLeeMesodermMiaomultidisciplinaryNaturenature.comscienceStem cell differentiationyannisYuchuanZhu
KHDK and Slipknot’s V-Man promise a “gritty as f**k” tone that will “change your life” with their new Totality overdrive,The limited-edition pedal is designed for both guitar and bass and boasts none-more-metal artwork crafted by Luke Preece Tags:Alessandro Venturellaguitarworld.comKHDKpedalsSlipknotV Man
Three ways moving on from Aaron Rodgers impacts Packers
Three ways moving on from Aaron Rodgers impacts Packers,Moving on from a franchise quarterback is a challenging situation for any NFL team. Here are three ways the Packers will be impacted if Rodgers has indeed played his last game as a member of the
DOH warns vs eating seafood from oil spill areas
DOH warns vs eating seafood from oil spill areas,The Department of Health warned the public yesterday against eating fish and other seafood from areas affected by the oil spill.
The post DOH warns vs eating seafood from oil spill areas appeared first
Washington turns to Wall Street to help rescue dying bank
Washington turns to Wall Street to help rescue dying bank,In a scene reminiscent of the last financial crisis, the federal government turned to Wall Street this week for help with a blossoming emergency in the banking sector
'Strays' director on making sure Will Ferrell flick is 'emotionally grounded' and not just R-rated spoof,On Wednesday, Universal Pictures introduced the world to Reggie, a happy-go-lucky Border Terrier with a heartwarming mission to find his way back home, reunite with his owner, and then ... *checks notes* bite off the man's ... *ahem* reproductive organ. Tags:ComedyDogsJamie FoxxMoviesStraysSYFY Official SiteSYFY WIRE Blog Postsyfy.comSYFYWIREUniversal PicturesWill Ferrell
'Raised by Wolves' showrunner breaks down Season 2 premiere, teases what's next on HBO Max series,In the Season 1 finale of Raised by Wolves two years ago, a new era was born as the androids, Mother (Amanda Collin) and Father (Abubakar Salim), survived their suicide mission to kill Mother's miraculous snake-baby as they landed safely on the planet's Tropical Zone. However, the creature was able to slink off into the wild — and that's a major problem for the Atheist Colony I residents. Tags:ExclusivesHBO MaxNewsRaised by WolvesSYFY Official SiteSYFY WIRE Blog Postsyfy.comSYFYWIREtv
MCU heroines (and one possible villain) who should have a Disney+ show,With a year's worth of Marvel Cinematic Universe Disney+ streaming series now out in the wild, the format has proven itself to be the place where characters, even smaller ones in the MCU, can finally get their expanded due. From Wanda Maximoff to Bucky Barnes, characters who had limited theatrical story real estate were given hours to develop and evolve far richer storylines. Tags:DisneyFeaturesHawkeyeListsMarvel Cinematic UniverseSYFY Official SiteSYFY WIRE Blog Postsyfy.comSYFYWIREtvYelena Belova
Doomsday who? Tyler Hoechlin opens up about that 'bizarre' villain twist on 'Superman & Lois',One of the benefits of a long-running shared small-screen storytelling landscape like the Arrowverse is the potential for new heroes and villains to constantly emerge, delighting longtime comics fans and surprising new viewers with reveals and developments with the potential to reverberate through each series for years to come. Tags:NewsSuperman u0026 LoisSYFY Official SiteSYFY WIRE Blog Postsyfy.comSYFYWIREThe CWtvTyler Hoechlin
'Knock at the Cabin' twist ending and post-credits sequence, explained,The central tension in M. Night Shyamalan's new film Knock at the Cabin is whether or not the four armed home invaders who take a family hostage are correct or not. They claim that, unless this family decides to willingly sacrifice one of themselves, the world will end. The family, naturally, thinks they’re either lying or crazy — or both. Tags:FeaturesKnock at the CabinM. Night ShyamalanMoviesSYFY Official SiteSYFY WIRE Blog Postsyfy.comSYFYWIRE
